THz-Raman® – The “Structural Fingerprint” of Raman
Ondax’s patented1 THz-Raman® Spectroscopy Modules extend the range of traditional Raman spectroscopy into the terahertz/low-frequency regime, exploring the same range of energy transitions as terahertz spectroscopy – without limiting the ability to measure the fingerprint
region. This region reveals a new “Structural Fingerprint” to complement the traditional “Chemical Fingerprint” of Raman, enabling simultaneous analysis of both molecular structure and chemical composition in one instrument for advanced materials characterization.
See What You’ve Been Missing – More Data, Better Sensitivity & Reliability
Clear real-time differentiation of structural attributes of the material enables clear identification and analysis of polymorphs, raw material sources, defects & contamination, crystal formation, phase monitoring and synthesis methods.
Features
• Compact optical design with integrated high power single frequency laser source
• Interchangeable sample interface - vial/tablet holder, steerable open beam, or contact probe tip
• Fiber coupled output enables easy interface to a wide range of spectrometers
• Fast collection of THz-Raman® spectra from 5cm-1 to >3000 cm-1 (150GHz to 90THz)
• Simultaneous Stokes and anti-Stokes signals improve SNR while providing inherent calibration reference
• Can be added on to an existing Raman system or spectrometer, or incoroporated into a complete turnkey system
• Available at 532nm, 785nm, 850nm, 976nm and 1064nm excitation wavelengths
Applications
• Polymorph identification and analysis
• CrystallizationMonitoring Studies and Reaction
• Trace detection and source attribution of explosives/hazmats/drugs
• Structural studies of nano- and bio- materials, photovoltaics, and semiconductors
• Forensics, archeology, mineralogy
One Sample, One System, One Answer
In-situ, real-time measurement of both composition and structural analysis eliminates the need for multiple samples and instruments, lowering capital, training and maintenance costs.
Benefits
• Both chemical composition + molecular structure from one Raman measurement
• In-situ, real-time structural monitoring + chemical analysis
• Higher SNR with inherent calibration reference
• Faster, more comprehensive and reliable measurements
• Compact, easy to use, and adaptable to existing Raman systems and spectrometers
Full Raman spectrum of the pharmaceutical Carbamazepine showing both the THz-Raman “Structural Fingerprint” and traditional “Chemical Fingerprint” regions. Note higher intensity and symmetry of THz-Raman signals.
Real-time monitoring of both structure and composition
THz-Raman® measurements capture low-frequency lattice and phonon modes that are manifested by both inter- and intra-molecular vibrations. These modes are highly responsive to changes in molecular structure and can be used to monitor structural changes caused by polymorphic or isomeric shifts, lattice defects, contaminants, and changes in phase or crystallinity. The examples below shows how THz-Raman can be used to obeserve polymorphic shifts, distinguish phase transformations, characterize co-crystalline mixtures, or determine synthetic pathways
Sample Interface AccessoriesA variety of sample interface accessories enable the TR-PROBE and TR-BENCH to be easily configured to match a broad range of applications. The Vial/Cuvette Sample Holder incorporates an adjustable steering mirror, interchangeable focusing lens, and safety shutter. Immersion or Contact probe tips may be mounted with either a fixed SwageLok mount or, for longer probes that may need alignment, an adjustable tip/tilt probe mount. And the Steerable Collimated Beam Mount allows for projection and steering of the collimated output beam with precision alignment and interchangeable focusing optics, for applications requiring long-range collection paths.
THz-Raman® TR-BENCH Module Specifications:
Parameter
Units
Specification
Wavelength
nm
532
785
850
Power at sample port (min)
mW
25 to 2501
60
60
Physical Dimensions (W x D x H)2
in
12” x 10” x3”
12” x 10” x3”
12” x 10” x3”
1 Specify power level at time of order
2 Base unit only, does not include sample accessory
Spectrometer3:
Fixed Grating Spectrometer
Tunable Grating Spectrometer
Spectral Range (typical)
-200cm-1 to +2200cm-1
400-1100 nm (w/Si Detector)
Spectral Resolution
2.5cm-1 to 4cm-1
0.7 cm-1 or greater
Computer Interface
USB
USB
3 Spectrometer selection and specifications will be determined by application requirements and options ordered
System Description and Configurations:
All TR-Series THz-Raman® modules are ultra-compact and simple to connect via fiber to almost any spectrometer or Raman system. Our patented SureBlock™ ultra-narrow-band Volume Holographic Grating (VHG) filters precisely block only the Rayleigh excitation with >OD8 attenuation, enabling simultaneous capture of both Stokes and anti-Stokes signals. A high-power, wavelength-stabilized, ASE-free single-frequency laser source is precisely matched to the filters to assure maximum throughput and exceptional attenuation of the excitation source.
The TR-MICRO mounts directly to a broad range of popular microscope platforms and micro-Raman systems, and can be easily switched in and out of the optical path. The system includes an Ondax SureLock™ 785nm, 850nm, or 976nm laser source, notch filters, and optional circular polarization (linear polarization is standard). A 532nm excitation source or a sample imaging camera are also available upon request.
The new TR-PROBE is a compact, robust THz-Raman® probe that enables in-situ reaction or process monitoring. The TR-PROBE can be configured with a variety of sample interface accessories, includine immersion or contact probe tips, a convenient vial/tablet holder, or a steerable collimated beam (see sample options on previous page).
The TR-BENCH is configured for benchtop use and offers the same range of interchangeable sample interface accessories holder for fast, easy measurements. The system also comes with a standard cage mounting plate (centered on the collimated output beam) to allow for customized collection optics or easy integration into a customized system. The TR-BENCH includes a SureLock™ 785nm, 850nm, or 976nm laser source, notch filters, and optional circular polarization.